tuberculosis
Infectious Diseases - 1 Answers
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When you are infected with a bacteria. (Mycobacterium tuberculosis) Your body will secrete substances called cytokines that activate other cells and processes in the body. A particular one called TNF-alpha causes you to get a fever. It causes your hypothalmus to "Set" your normal temperature higher than normal, say 99.4 instead of 98.6. This new "set" on your internal thermostat means your body will defend itself against a change to this temperature, just like it would defend against a normal temperature. If it gets cold in a room and you chill, its because the area your in is causing your body to loose more heat than it can replace so you "feel cold". If you have a fever, and your normal temperature is "Set" higher, then you will get "chills" easier. Somone with a normal temperature will think 72 degress is fine because their temperature is 98.6. The person with a fever will think 72 degrees is cold because their temperature is 99.5 or better. Hope this helps
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